Los Angeles, CA, February 26, 2009 – The results of a clinical trial investigating the bioavailability of Jarrow Formulas’ QH-absorb, a stabilized proprietary Co-Q10 formula utilizing the reduced form of Co-Q10 called ubiquinol, on 11 adult volunteers, was recently concluded at the medical school of the University of Ancona in Ancona, Italy.
Italian scientists from the University of Ancona (Institute of Biochemistry) measured the plasma level of Co-Q10 after taking 100 mg three times per day (100 mg T.I.D. = 300 mg). Eleven adult volunteers took Jarrow Formulas’ proprietary QH-absorb formula over a 2-week period.
In this study, the results proved the superior absorption of QH-absorb, as demonstrated by:
• total Co-Q10 levels increasing from 0.70 mcg/mL to 6.14 mcg/mL.
• improving the mean reduced Co-Q10 (ubiquinol) levels in the plasma from .62 mcg/ml to 5.75 mcg/mL. This was an increase of 827 percent over baseline in humans.
• 5 of the volunteers achieved plasma levels over 7 mcg/mL and one subject was higher than 8 mcg/mL.
Another interesting finding showed a significant reduction in oxidized Co-Q10 in patients. Oxidized Co-Q10 does not function as an antioxidant. The results proved the efficacy of QH-absorb as demonstrated by a reduction in the mean oxidized Co-Q10 levels in the plasma from 12 percent to 7 percent.
Jarrow L. Rogovin, President of Jarrow Formulas, described another finding of the study. “Not only did our QH-absorb increase plasma Co-Q10 levels two to three times more than other QH formulas, it also decreased the percentage of plasma oxidized Co-Q10 by 45 percent. It significantly increased the antioxidant, QH2, form of ubiquinol in the body. That is incredibly exciting for people watching their heart health or blood sugar.”
Jarrow Formulas’ QH-absorb is a proprietary stabilized formula that offers improved bioavailability over standard Co-Q10 supplements (ubiquinone), and is able to deliver Co-Q10 in its native antioxidant-capable form at higher levels. While standard Co-Q10 (ubiquinone) supplements can be reduced to the antioxidant state in the body, this reduction can be less efficient in some individuals due to health status, age or genetics. Ubiquinol also has significantly superior bioavailability to ubiquinone as demonstrated in clinical trials.
QH-absorb, like Q-absorb, uses an all-natural proliposome delivery system to improve absorption. Jarrow Formulas’ Q-absorb and QH-absorb delivery systems have been validated in multiple trials to significantly improve Co-Q10 absorption over other Co-Q10 formulas. Jarrow Formulas’ ubiquinol is derived from Co-Q10 that is manufactured via a yeast-fermentation process and consists only of the natural trans configuration, the same as is biosynthesized by humans.
Jarrow Formulas is a direct contributor to research on CoQ10. It has funded several clinical trials on the nutrient, as well as acts as a sponsor for the international society that promotes research and education regarding coenzyme Q10.