Technological innovations have significantly influenced injury management and recovery in the continuously advancing domain of sports medicine and rehabilitation.
The incorporation of laser therapy, vibration therapy and pneumatic compression devices presents promising advancements that enhance the outcomes of injury care and recovery. This article conducts a thorough examination of each technology, critically assessing and analyzing existing research to provide insights into each one’s efficacy and prospective applications.
Laser therapy for injury care in clinical practice: Mechanisms and applications of photobiomodulation
The incorporation of laser therapy into rehabilitation and manual therapy practices has significantly expanded over the past decade, providing an evidence-based, noninvasive modality for injury care, inflammation and tissue repair. Of the various laser technologies used in therapeutic settings, low-level laser therapy (LLLT) and superpulsed laser therapy have emerged as clinically valuable instruments for addressing both superficial and deep musculoskeletal conditions through the process of photobiomodulation.
Mechanisms of action: Low-level vs. superpulsed laser therapy
LLLT, commonly referred to as cold laser therapy, uses red to near-infrared light wavelengths (typically ranging from 600 to 1,000 nm) to initiate a cascade of photochemical processes within targeted tissues. At the cellular level, LLLT influences mitochondrial activity by stimulating cytochrome c oxidase, a key enzyme in the electron transport chain. This activation leads to increased production of adenosine triphosphate (ATP), modulation of reactive oxygen species (ROS) and upregulation of transcription factors responsible for cellular repair and anti-inflammatory activity.1,2 Importantly, LLLT produces these effects without generating thermal damage, making it a safe option for a broad range of clinical populations.
In contrast, superpulsed laser therapy uses extremely brief (in the nanosecond range), high-peak-power pulses of light that enable greater tissue penetration while maintaining a low average thermal output. This allows the treatment of deeper anatomical structures, such as large muscle groups and joint capsules, without the risk of overheating or tissue damage.3
Clinical applications and current evidence
For DCs, physical therapists and athletic trainers, laser therapy offers an option that aligns with contemporary objectives of minimizing pharmacologic interventions and expediting patients’ return to activity. Clinical evidence substantiates the use of LLLT for tendinopathies, osteoarthritis, chronic low back pain and delayed wound healing, with research indicating reductions in pain intensity, enhancements in functional measures and improvements in tissue regeneration.4,5
Superpulsed laser therapy has exhibited particular efficacy in the treatment of acute soft tissue injuries, ligament sprains, deep muscle strains and joint pathologies, where its capacity for deeper penetration facilitates the modulation of inflammation and the stimulation of microcirculatory repair processes. In clinical practice, this enables targeted treatment of tissue structures frequently beyond the reach of traditional modalities, such as superficial thermotherapy or manual soft tissue techniques.6
Integration into clinical workflow
Incorporating laser therapy into musculoskeletal rehabilitation requires consideration of dosage parameters, tissue depth and the specific physiologic goals of treatment. DCs are encouraged to include photobiomodulation as part of an integrated plan of care, particularly when managing patients with complex pain, inflammation or delayed healing. Furthermore, the noninvasive and analgesic nature of laser therapy makes it suitable for patients with contraindications to more aggressive manual interventions or those seeking alternatives to pharmacological pain management.
Vibration therapy
Applications and devices
Vibration therapy (VT) uses mechanical oscillations to stimulate muscle and bone density and is increasingly employed in rehabilitation settings. Some devices provide percussive therapy, purporting to enhance flexibility, increase blood circulation and diminish muscle stiffness. VT is a viable option to augment physical performance and mitigate the adverse effects of aging on bones, muscles and tendons. Two primary categories of vibrating devices exist: whole-body vibration (WBV) devices and vibration devices localized to a single muscle.7
Purported benefits and potential drawbacks
The benefits of VT include enhanced neuromuscular performance and accelerated muscle recovery, partially attributed to rapid muscle contractions induced by vibrations. VT can provide anabolic mechanical signals to bone and the musculoskeletal system. However, its efficacy can vary, and excessive use may lead to muscle soreness or cardiovascular strain, highlighting a need for tailored application based on individual response.9 Discrepancies exist on the ideal applications, frequency and magnitude of VT, reflecting the contradictory clinical results in the literature.
Scientific evidence
A variety of studies have demonstrated the effectiveness of VT in enhancing muscle recovery following exercise, including a meta-analysis that showed substantial improvements in muscle discomfort and recovery time following VT.10 Despite these positive indicators, additional research is required to standardize protocols across various populations and conditions.
The vibration frequency of WBV applications is 20-50 Hz, while local applications to a specific muscular district can tolerate a much higher frequency range, approximately 300-500 Hz. Pain control, increased bone density, accelerated rehabilitation, reduced fatigue onset, improved muscle force and flexibility and pain reduction are among the most frequent therapeutic goals of VT use.
Clinical applications
- Muscle soreness: WBV has been shown to decrease delayed-onset muscle soreness (DOMS) and tightness while increasing flexibility and muscle power.11,12,13,14
- Elderly patients: VT can help attenuate the normal senescence process, which involves decreases in muscular performance, balancing ability, coordination and bone density.
- Bone metabolism: VT improves bone circulation, increases the supply of nutrients needed to build bones, promotes osteogenic differentiation and reduces osteoclast formation.
Technical considerations
Multiple devices are used in clinical trials, with different directionality (horizontal displacement, side-to-side or vertical), amplitudes and frequencies. It is recommended to use devices that clearly report vibration parameters and deliver low-intensity (<1 g), horizontal displacements at high frequencies (30-100 Hz).
VT provides anabolic mechanical signals to bone and the musculoskeletal system, mimicking motion and exercise while positively influencing muscle function and coordination. While these technological advances offer significant promise, they must be used with a nuanced understanding of individual patient needs, grounded in robust evidence-based practice. Further research is essential to optimize their application.
Pneumatic compression devices
Role and mechanisms
Pneumatic compression devices (PCDs) apply external pressure to limbs to enhance venous return and reduce inflammation and muscle soreness. These devices are increasingly being integrated into athletic recovery regimens.
Physiological effects and applications
The primary physiological effect of PCDs is the improvement of lymphatic drainage and reduction of edema, leading to decreased recovery time and improved muscle healing/injury care.15 Common applications include use after intensive training sessions and surgeries to mitigate DOMS. Research suggests PCDs may be beneficial in preventing postoperative complications, such as operative site edema, distal limb edema, wound dehiscence and tissue necrosis.16 However, other research shows use of PCDs did not alter the rate of muscle glycogen resynthesis, blood lactate or blood glucose and insulin concentrations associated with a post-exercise oral glucose load.17
Relevant research findings
A systematic review indicates that PCDs can significantly reduce muscle soreness and enhance performance recovery, though individual differences in response remain a factor.18 However, recent studies question the effectiveness of intermittent pneumatic compression (IPC) for reducing exercise-induced muscle damage (EIMD) in endurance athletes.19 While IPC may provide immediate pain relief, it does not appear to offer continued injury care/relief from EIMD.
Research indicates that muscle glycogen increased similarly over the recovery period for both PCD and passive recovery trials, suggesting PCDs do not significantly impact glycogen resynthesis. Similarly, other reports found that IPC did not benefit recovery following prolonged running, with no significant effects on C-reactive protein (CRP) or perceived pain.20
While pneumatic compression devices show promise in enhancing recovery, injury care, and preventing postoperative complications, the evidence regarding their effectiveness in reducing EIMD and improving glycogen resynthesis is mixed. Further research is needed to optimize their application and understand their long-term benefits and limitations.
Evidence-based practice: Navigate the technology surge
It is our responsibility as rehabilitation professionals to critically evaluate emerging technologies through the lens of evidence-based practice. The finest available evidence, clinician expertise and patient values are all factors we must take into account. Innovation’s allure can be compelling; however, novelty should not be substituted for necessity.
The potential of laser therapy, vibration therapy and pneumatic compression has been demonstrated in specific contexts. Nevertheless, these modalities’ efficacy is not universal, and none should be considered a panacea. Integrating these technologies with interventions that have been proven effective for injury care, including patient education, manual therapy and therapeutic exercise, is still crucial.
Additionally, there is a lack of standardized protocols for application. The interpretation of clinical outcomes is complicated by the variability in device parameters, session frequency and patient selection. This serves to emphasize the necessity of personalized care plans that are based on continuous evaluation and clinical reasoning.
Future directions: Innovation with intention
The future of injury care and recovery will become more personalized, data-driven and integrated as we look ahead. To improve clinical decision-making, wearable sensors, AI-assisted diagnostics and biofeedback platforms are currently being investigated. The next decade is expected to bring about a new frontier in musculoskeletal rehabilitation, combined with advanced technologies, such as neuromodulation, robotics and regenerative medicine.
However, it is imperative technologies undergo stringent testing in real-world clinical settings, with outcome measures that are relevant to patients, including pain relief, functional improvement and return to activity. Research priorities should encompass cost-benefit analyses, long-term outcome monitoring and large-scale randomized trials.
Brian V. Hortz, PHD, ATC, SFDN, is director of research and education at Structure and Function Education. For more information, email brian@structureandfunction.net or visit structureandfunction.net.
References
- Chow RT, et al. Efficacy of low-level laser therapy in the management of neck pain: A systematic review and meta-analysis of randomized placebo or active-treatment controlled trials. Lancet. 2009;374(9705):1897–1908. https://pubmed.ncbi.nlm.nih.gov/19913903/ . Accessed June 17, 2025.
- Chung H, et al. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012;40(2):516–533. https://pubmed.ncbi.nlm.nih.gov/22045511/. Accessed June 17, 2025.
- Cotler HB, et al. The use of low-laser therapy (LLLT) for musculoskeletal pain. MOJ Orthop Rheumatol. 2015;2(5):00068. https://pubmed.ncbi.nlm.nih.gov/26858986/. Accessed June 18, 2025.
- Bjordal JM, et al. A systematic review of low-level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother. 2003;49(2):107–116. https://pubmed.ncbi.nlm.nih.gov/12775206/. Accessed June 17, 2025.
- Enwemeka CS, et al. The efficacy of low-power lasers in tissue repair and pain control: A meta-analysis study. Photomed Laser Surg. 2004.;22(4):323–329. https://pubmed.ncbi.nlm.nih.gov/15345176/. Accessed June 17, 2025.
- De Oliveira MF, et al. Low-intensity laser and LED (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions. Eur J Phys Rehabil Med. 2022;58(2):282-289. https://pubmed.ncbi.nlm.nih.gov/34913330/#full-view-affiliation-1. Accessed June 17, 2025.
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- Rittweger J. Vibration as an exercise modality: How it may work and what its potential might be? European Journal of Applied Physiology. 2010;108:877-904. https://link.springer.com/article/10.1007/s00421-009-1303-3. Accessed June 18, 2025.
- Pojskic H, et al. Acute effects of loaded whole body vibration training on performance. Asian J Sports Med. 2015;6(1):e24054. https://pubmed.ncbi.nlm.nih.gov/25883774/. Accessed June 18, 2025.
- Lau WY, Nosaka K. Effect of vibration treatment on symptoms associated with eccentric exercise-induced muscle damage. Am J Phys Med Rehab. 2011;90(8):648–657. https://pubmed.ncbi.nlm.nih.gov/21273897/. Accessed June 17, 2025.
- Rhea MR, et la. Effect of iTonic whole-body vibration on delayed-onset muscle soreness among untrained individuals. J Strength Cond Res. 2009;23(6):1677–1682. https://pubmed.ncbi.nlm.nih.gov/19675497/. Accessed June 17, 2025.
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- Aminian-Far A, et al. Whole-body vibration and the prevention and treatment of delayed-onset muscle soreness. J Athl Train. 2011;46(1):43–49. https://pubmed.ncbi.nlm.nih.gov/21214349/. Accessed June 17, 2025.
- Koh HW, et al. Effects of vibratory stimulations on maximal voluntary isometric contraction from delayed onset muscle soreness. J Phys Ther Sci. 2013;25(9):1093–1095. https://pubmed.ncbi.nlm.nih.gov/24259922/. Accessed June 17, 2025.
- Stedge HL, Armstrong K. The effects of intermittent pneumatic compression on the reduction of exercise-induced muscle damage in endurance athletes: A critically appraised topic. J Sport Rehabil. 2021;30(4):668-671. https://pubmed.ncbi.nlm.nih.gov/33418535/. Accessed June 18, 2025.
- Talbot SG, et al. Case report Postoperative use of the NormaTec pneumatic compression device in vascular anomalies. Eplasty. 2012;12:e5. https://pubmed.ncbi.nlm.nih.gov/22292102/. Accessed June 17, 2025.
- Keck NA, et al. Effect of lower limb compression (NormaTec) on glycogenresynthesis. 2012:1396. Graduate Student Theses. [Dissertations, Professional Papers]. https://scholarworks.umt.edu/etd/1396. Accessed June 18, 2025.
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- Draper SN, et al. Effects of intermittent pneumatic compression on delayed onset muscle soreness (DOMS) in long distance runners. Int J Exerc Sci. (2020;13(2):75–86. https://pubmed.ncbi.nlm.nih.gov/32148616/. Accessed June 17, 2025.