TruGen3’s® TruDerma Health®, exclusively formulated by Dr. Justin Vujevich, MD, FAAD, Dermatologist, is the first supplement that combines clinically researched skin health vitamins and minerals into one product.
Many patients understand the importance of skin precautionary measures and regular use of sunscreen for sound skin, yet some may not recognize the significance of these specific vitamins and minerals that defend within.
Niacinamide is the physiologically active, water-soluble amide form of niacin (vitamin B3). Niacinamide is a precursor to niacinamide adenine dinucleotide (NAD) and niacinamide adenine dinucleotide phosphate (NADP). NAD and NADP support cellular energy production and act as coenzymes for biochemical reactions in the body. Niacinamide has been shown to maintain the skin through its ability to inhibit physiological mediators that play a role in ultraviolet radiation-induced DNA damage. In a double-blinded controlled trial, patients received oral niacinamide 500mg or placebo twice a day for four months. Niacinamide supplementation resulted in a 35% reduction in skin damage caused by UV sunlight exposure compared to the placebo group.
Biotin, also known as vitamin H and coenzyme R, is a cofactor that is paramount to several enzymes involved in carbohydrate metabolism, fatty-acid synthesis and protein formation. Biotin supplementation demonstrated increased hair growth and healthy skin in infants with biotin deficiency.
Vitamin D, generally called the “sunshine vitamin”, assumes a critical role in the proper functioning of the body. Social standards and other industry support sun tanning or indoor tanning as a wellspring of vitamin D. The U.S. Branch of Health and Human Services and the World Health Organization strongly encourage obtaining vitamin D through diet and supplementation to ensure adequate vitamin D status. Supplementing with vitamin D may eliminate unnecessary sun exposure as the main source for vitamin D synthesis.
In addition to sun exposure, the body is constantly threatened by damage created from normal oxygen metabolism, and by other chemical reactions. Selenium and zinc are two basic trace elements that provide protection against reactive oxygen species such as free radicals, peroxides, and lipid peroxides by means of their strong antioxidant activity. Selenium is a cofactor for glutathione peroxidase (GPX). The selenium-glutathione peroxidase pathway protects against damage to cellular components. Animal and human studies have found that oral selenium built up assurance against ultraviolet-induced damage to skin cells. Zinc’s cell reinforcement properties support the removal of free oxygen radicals in the body produced after-ultraviolet exposure.
Vitamin C is among the most powerful antioxidants in humans. Vitamin C is required for the synthesis of collagen and glycosaminoglycans, which are the structural components of all connective tissues, for example, skin, tendons, joint cartilage, bone, and blood vessels. In the skin, vitamin C is an effective inhibitor of the generation of reactive oxygen species, particularly after ultraviolet light exposure.