Low level laser therapy effects on muscle healing after cryolesion

Brunelli RM, Rodrigues NC, Ribeiro DA, Fernandes K, Magri A, Assis L, Parizotto NA, Cliquet A Jr, Renno AC, Abreu DC. Post Graduation Program of Surgery, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.

Lasers Med Sci. 2013 Feb 14. [Epub ahead of print]

Abstract

The objective of this study was to assess the effects of 780-nm low level laser therapy at different periods of 7, 14 and 21 days after cryolesion, including the dose (10 or 50 J/cm(2)), to promote a better muscle repair evidenced by histopathological and immunohistochemical analyses. Fifty-four male rats were divided into three groups: injured control group (CG)-injured animals without any treatment; injured 780-nm laser-treated group, at 10 J/cm(2) (G10); and injured 780-nm laser-treated group, at 50 J/cm(2) (G50). Each group was divided into three subgroups (n?=?6): 7, 14 and 21 days post-injury. Histopathological findings revealed better organised muscle fibres in the G10 and G50 during the periods of 7 and 14 days compared to the CG. The G10 and G50 during the 7 days showed a significant reduction (p?