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July
2004
NIH funds clinical trials of chromium
picolinate
The Yale-Griffin Prevention Research Center
(PRC), a collaboration between Griffin Hospital and the Yale
School of Epidemiology and Public Health, announced the start
of a double-blind, randomized, placebo-controlled clinical
trial to study the effects of chromium supplementation on
blood glucose levels and endothelial function in people with
pre-diabetes. The two-year pilot study is funded by a grant
from the National Institutes of Health's (NIH) National Center
for Complementary and Alternative Medicine (NCCAM).
"The aim of this clinical trial is
to further explore the benefit of nutritional intervention
with chromium picolinate, before pre-diabetes progresses into
a chronic disease state," explains Dr. David Katz, director
of the Yale-Griffin Prevention Research Center and principal
investigator of the new study. "In pre-diabetes, pharmacotherapy
may not yet be justified or acceptable for patients. Chromium
has shown potential to serve as a safe and affordable adjunct
nutritional therapy, as part of a preventive approach."
Pre-diabetes, also known as Impaired Glucose
Tolerance (IGT), affects approximately 41 million Americans
and is a pre-cursor to type 2 diabetes and cardiovascular
disease. The American Diabetes Association (ADA) defines pre-
diabetes as a condition in which blood sugar levels are higher
than normal, but not high enough to be diagnosed as type 2
diabetes.
Source: Yale-Griffin Prevention Research
Center
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